Who is responsible for reviewing pesticides on a 15-year cycle?

The Environmental Protection Agency (EPA) is responsible for reviewing pesticides on a 15-year cycle as part of its mandate to ensure that pesticides used in the United States do not pose an unreasonable risk to human health or the environment. This periodic review process, known as re-registration, involves evaluating the safety and efficacy of existing pesticides based on the latest scientific research and advances in technology. The process ensures that any emerging risks associated with pesticide use are identified and addressed, and it allows for the modification or revocation of pesticide registrations if deemed necessary.

In this context, while the Department of Agriculture plays a significant role in the regulation and enforcement of pesticide use at the state level, it does not conduct the comprehensive reviews on a national scale as the EPA does. Similarly, state pesticide boards may oversee local compliance and licensing, while commercial pesticide applicators are responsible for applying pesticides safely but do not have the authority or responsibility for regulatory reviews. Therefore, the EPA's role in the systematic review of pesticides every 15 years makes it the correct answer.